Again, the best buying opportunity must be when most people are unwilling, afraid, and don't know how to buy.
You must understand a simple truth when speculating in cryptocurrencies, that is, the dealer will never let retail investors sit in the car to help you pull first. He needs to let you get off the car first, and then drive away by himself, letting you chase. So the best opportunity is when he is urging passengers to get off the car.
When will the passengers get off the car?
When the driver drives in the opposite direction, tells you that there is a problem with the car, when the weather is bad...
When will retail investors sell?
When the founder or team is in trouble, when there is a major negative, when the price of the currency plummets at a low level...