ETH's tenth anniversary, there is a free NFT minting on the official website, everyone hurry, only one day's time. I originally thought the network fees would be high, but it turns out the chain is not active now, the average fee is only about $0.3, and then I checked BTC's network fee is also similar, the price is rising, is the transfer fee so low? Then it can really replace the swift system, it can be seen that after being bear for so long, the enthusiasm on the chain has dissipated, only the operation of waiting for coins to rise is left, or have already played memes and lost and laid flat. Back to the point, the project introduced today is relatively niche, but I personally feel it has great development potential in the future, it's just that under the current world system, it takes a long way to achieve this, cherish every step.


The BIO Protocol is a decentralized science (DeSci) platform aimed at innovating the funding, development, and intellectual property (IP) sharing mechanisms of traditional biomedical research through blockchain technology and decentralized autonomous organization (DAO) models. What is DeSci? A brief introduction to the DeSci concept. Below is a detailed introduction to its project status and future development direction analysis.

1. BIO Protocol project status

1. Project background
The origin of the BIO Protocol can be traced back to its core team's early experiences with the biomedical tokenization platform Molecule and the longevity science community VitaDAO. In early 2023, the team began building the DeSci ecosystem and officially launched the BIO Protocol in 2024 to address issues such as uneven funding distribution, lack of research transparency, and intellectual property silos in traditional scientific research.

- Core goal: Accelerate the inflow of capital and talent into the biotechnology field through decentralized financial and governance mechanisms, with a focus on supporting cutting-edge areas such as rare diseases, longevity research, women's health, neurodegenerative diseases, and synthetic biology.
- Core mechanism: The BIO Protocol promotes transparency, verifiability, and efficiency in biotechnology research and commercialization through a network of BioDAOs (Decentralized Scientific Autonomous Organizations), IP tokenization (IP-Token mechanism), on-chain liquidity support, and meta-governance structures.

2. Project progress
- November 2024: Binance Labs announces its first DeSci investment in the BIO Protocol, marking industry recognition and funding support for the project.
- December 2024: The BIO Protocol completes the BIO Genesis token issuance, raising over $33 million and launching the BIO token airdrop plan to attract global scientists, patients, and investors to participate and enhance community vitality.
- January 2025: The BIO token is launched on Binance Launchpool and plans to circulate on multi-chain networks such as Ethereum, Solana, and Base, expanding the market coverage and influence of the token.
- July 2025: Coinbase announces its inclusion of the BIO Protocol in its asset roadmap, further enhancing the project's visibility in the crypto market.
- Recent developments: The BIO Protocol announces the upcoming launch of BioAgent (AI-based research tool), BioXP (experimental platform), and Launchpad V2 (upgraded project incubation mechanism), indicating that the project is moving towards broader technological integration and ecosystem expansion.

3. Core functions and mechanisms


- BioDAOs: The core component of the BIO Protocol is BioDAOs, each focusing on a specific scientific field (such as longevity, women's health, neurodegenerative diseases, etc.). Currently, the network includes:
- VitaDAO: Longevity science field, raised over $5 million, in collaboration with Pfizer Ventures and Newcastle University.
- HairDAO: Focused on hair loss, with patents and consumer products.
- CerebrumDAO: Brain health research, raised $1.5 million, focusing on neurodegenerative diseases.
- ValleyDAO: Synthetic biology, in collaboration with Imperial College London.
- AthenaDAO: Women's health research, with 14 pending intellectual property transactions.
- Emerging DAOs such as Quantum Biology DAO, Long COVID Labs, Curetopia, focusing on quantum biology, long COVID, and rare disease research, respectively.
- IP-Token mechanism: Each intellectual property asset is tokenized, possessing an independent token that defines ownership and trading rules, allowing users to obtain partial or full IP ownership through trading.
- Liquidity support: The BIO Protocol provides on-chain liquidity management for BioDAOs, alleviating the market operation burden on DAOs and ensuring token liquidity and market value.
- Meta-governance structure: BIO token holders participate in the approval and governance of new BioDAOs through staking (vBIO), influencing fund allocation and research direction, ensuring coordinated development within the ecosystem.
- Token economics:
- Total supply: 3.32 billion BIO tokens. Current price $0.07, FDV $242 million. Originally on the ETH chain, but due to high transaction fees, it was expanded to Solana and Base chains.
- Initial circulation: Approximately 1.3 billion (39.05%).
- Distribution: 56% for ecosystem and community, 25.4% allocated to early contributors (6-year linear unlock), 18.6% allocated to early supporters (4-6 year linear unlock).
- Token functions: Governance, support for new BioDAO projects, allocation of network resources.

4. Core team


The team of the BIO Protocol consists of seasoned experts in the fields of blockchain and biotechnology:
- Paul Kohlhaas: Co-founder, founder and CEO of Molecule, co-founder of VitaDAO, previously worked at ConsenSys and Swiss government blockchain projects.
- Clemens Ortlepp: Co-founder and Chief Product Officer, founder of MTX Studio, focusing on user-end product development.
- James Sinka: Responsible for blockchain technology and community operations, ensuring the stability of the technical architecture and promoting community ecosystem development.
- Jose Pinto: Legal advisor, well-versed in legal regulations in the cryptocurrency field, ensuring the project's compliance.

5. Market performance and community response


- Market performance: After the BIO token was launched on Binance Launchpool, related DeSci tokens (such as VITA, RSC, RIF, DRUGS) have seen significant increases, reflecting strong market interest in the DeSci field.
- Community support: Through airdrops and multiple rounds of auctions, the BIO Protocol has built a highly engaged global community. Founder Paul Kohlhaas donated $690,000 worth of BIO tokens to the Big Pharma community, further incentivizing community development.
- Industry recognition: Support from Binance Labs and Coinbase indicates the BIO Protocol's leading position in the DeSci field, with the market likening it to a 'Y Combinator of on-chain science.'


2. Future development direction analysis

1. Technology and ecosystem expansion


- AI and blockchain integration: The BIO Protocol plans to integrate AI technologies through BioAgent and BioXP to support scientific discovery and automate experimental processes. For example, BioAgent can be used for data analysis and research optimization, while BioXP may provide an interactive experimental platform to enhance research efficiency.
- Multi-chain ecosystem: BIO tokens are already circulating on Ethereum, Solana, and Base networks, and may further expand to other blockchains in the future, enhancing cross-chain interoperability and market coverage.
- Launchpad V2: The upgraded project incubation mechanism will optimize the launch process of BioDAOs, attract more high-quality scientific projects to join the network, lower the entry threshold, and improve funding efficiency.

2. Expansion of scientific research fields


- Emerging fields: The BIO Protocol has established BioDAOs in fields such as longevity, women's health, and neurodegenerative diseases, and may further cover cutting-edge areas such as quantum biology, synthetic biology, and rare diseases in the future. For example, the quantum microscopy research of Quantum Biology DAO and the post-COVID research of Long COVID Labs show high potential.
- Global scientific collaboration: By sharing standardized experimental protocols (such as molecular biology, CRISPR technology, single-cell analysis, etc.), the BIO Protocol aims to become the 'GitHub of the biological world', enhancing the reproducibility and transparency of global scientific research.

3. Funding and community growth


- Continuous funding: Following the investment from Binance Labs and the $33 million token issuance, the BIO Protocol may attract more institutional investments (such as venture capital or pharmaceutical giants), further expanding its funding pool.
- Community incentives: Through token airdrops, governance participation, and IP tokenization, the BIO Protocol will continue to incentivize scientists, patients, and investors to participate, building a diverse community. The airdrop plan and meta-governance mechanism will enhance community engagement.
- Meta-governance optimization: Through vBIO staking and meta-governance, the BIO Protocol can coordinate research directions and resource allocation across multiple BioDAOs, and may introduce more complex governance models in the future, such as AI-based decision support systems.

4. Challenges and responses


- Regulatory challenges: The intellectual property and data privacy issues in the biotechnology field involve complex global regulations. The legal advisory team of the BIO Protocol must ensure compliance, especially in token issuance and IP transactions.
- Technological stability: The application of blockchain technology in scientific research still needs to validate its stability and security. The BIO Protocol needs to continuously optimize its public chain architecture, reduce transaction costs, and improve efficiency.
- Market competition: The DeSci field is gradually heating up, with projects like Pump Science and GLP1 also rising. The BIO Protocol needs to leverage its first-mover advantage and the backing of Binance and Coinbase to solidify its market position.

5. Long-term vision


- Reshaping the research paradigm: The BIO Protocol aims to break the traditional pharmaceutical and research 'valley of death' (where early projects fail due to lack of funding) through decentralized finance and governance, promoting open and transparent scientific collaboration.
- Social impact: By supporting breakthroughs in fields such as rare diseases, longevity, and women's health, the BIO Protocol aims to provide innovative solutions to global health challenges and enhance social welfare.
- DeSci ecosystem leader: As a leader in the DeSci field, the BIO Protocol is expected to become a benchmark for on-chain scientific research, similar to Uniswap or Aave in the DeFi space, driving the entire industry towards decentralization.

3. Summary


The BIO Protocol is an innovative platform that combines blockchain, AI, and biotechnology, addressing issues such as uneven funding distribution and lack of transparency in traditional scientific research through BioDAOs, IP tokenization, and meta-governance mechanisms. Backed by Binance Labs and Coinbase, market performance and community participation continue to rise. In the future, the BIO Protocol is expected to further consolidate its leadership position in the DeSci field through technological upgrades, field expansion, and community incentives, becoming a hub for global scientific collaboration and funding flow. However, regulation, technological stability, and market competition remain critical challenges in its development.

Suggestions: Pay attention to the technological updates of the BIO Protocol (such as the launch of BioAgent and BioXP) and the auction dynamics of new BioDAOs to seize ecosystem expansion and investment opportunities. For researchers, utilizing standardized experimental protocols and community resources can enhance research efficiency and reproducibility.

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