Centralized Exchanges (CEXs) like Binance offer ease of use, high liquidity, and fast trades, but they hold your funds, which means you need to trust the platform. Decentralized Exchanges (DEXs) like Uniswap, on the other hand, give you full control over your crypto. No KYC, no third-party custody. However, DEXs may have less liquidity and slower transactions. CEXs are better for beginners; DEXs appeal to privacy lovers and DeFi enthusiasts. Each has trade-offs, the best choice depends on your goals and trust level in crypto platforms.