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Top 15 U.S.-Based Crypto Projects to Watch in 2025
These American Web3 pioneers are reshaping the crypto landscape:
1. Chainlink ($LINK) – The undisputed leader in decentralized oracles
2. Uniswap ($UNI) – America’s original DEX driving DeFi innovation
3. Coinbase (Base / $COIN) – A crypto gateway and Layer 2 innovator
4. Circle (USDC) – A trusted, globally adopted stablecoin
5. Avalanche ($AVAX) – High-speed Layer 1 with institutional backing
6. The Graph ($GRT) – The indexing layer powering Web3 data
7. Arbitrum ($ARB) – Scalable and cost-efficient Ethereum Layer 2
8. Optimism ($OP) – A future-focused L2 scaling Ethereum
9. Stacks ($STX) – Enabling smart contracts on Bitcoin
10. Helium ($HNT) – Decentralizing IoT, now running on Solana
11. dYdX ($DYDX) – A pro-grade DeFi derivatives platform
12. Compound ($COMP) – A foundational player in DeFi lending
13. Aavegotchi ($GHST) – Gaming meets DeFi with U.S. development roots
14. Synthetix ($SNX) – Onchain trading powered by synthetic assets
15. UMA ($UMA) – Creating decentralized truth verification protocols
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