$USDC First of all, it is important to note that USDC was initially established on the Ethereum blockchain, which means it uses Ethereum's decentralized technology for its transactions and records. As an ERC-20 token, it is interoperable with a multitude of ERC-20 compatible wallets and platforms, greatly facilitating its management and exchange for users. However, in a development logic, Circle has made USDC natively available on eleven different blockchains (Ethereum, Algorand (Algorand course), Arbitrum, Avalanche, Flow, Hedera, Solana, Stellar, TRON, OP Mainnet, and Base).