$USDC $ ##USDT pair

The "best" coin pair with USDC really depends on your trading goals, platform, and risk appetite. That said, two of the most popular and liquid pairs are:

**USDC/ETH Pair**

Pairing USDC with Ethereum (ETH) is very common because ETH not only has high liquidity, but is also central to the decentralized finance (DeFi) ecosystem. Trading through the USDC/ETH pair gives you access to a wide range of DeFi applications and trading opportunities across multiple platforms and blockchains.