the truth is, I do notice.
I simply choose to focus on comments with a more interesting take or genuinely just very early comments.
for example, I can't respond gm to all 500 gm comments, but I can to the first 25-50 :)
similarly, out of 150 comments asking me stuff, I can pick the ones that make the most sense.
so, e.g. if you ask a very basic/beginner question, and very late into the tweet I might not reply to u at all. (because 50 ppl asked the same thing, make no sense for me to keep repeating too)
perspective, my brother.
ask me a good question; if I see it, I'll almost always reply.
(I respond to 200 to 300+ comments every day.)