While the crypto market is still debating 'whether Ethereum is undervalued,' billionaire Peter Thiel's latest moves provide a clear answer. On August 12, SEC documents disclosed that Peter Thiel and his team acquired 7.5% of Ethereum treasury reserve company ETHZilla (formerly a biotechnology company 180 Life Sciences). This news not only led to ETHZilla's stock price rising by over 11% on the day but also soared 55% in after-hours trading, sending new signals to the market about institutional layouts in Ethereum.

1. From biotechnology to Ethereum reserves: ETHZilla's cross-border ambitions.

ETHZilla's transformation can be described as a 'glorious turnaround.' This company, originally named 180 Life Sciences (stock code ATNF), announced the 'Ethereum treasury plan' at the end of July and has been active in just half a month:


  • Completed a $425 million private placement, immediately followed by the sale of $156 million in senior secured convertible notes due in 2028 to institutional investors;

  • The raised funds are clearly directed towards three major areas: purchasing Ethereum, laying out income-generating crypto assets, and expanding online gambling (iGaming) businesses, while monetizing existing biotechnology intellectual property.


This cross-border transformation is not coincidental. Against the backdrop of crypto assets gradually being recognized by traditional capital, traditional companies are cutting into the crypto track through 'acquisition + transformation,' which has become a shortcut for low-cost layout. The core logic of ETHZilla is clear: using 'Ethereum reserves' as a anchor, combining the compliant shell resources of traditional public companies with the growth potential of crypto assets to create 'compliant crypto vehicles.'

2. Peter Thiel's crypto chess game: Why Ethereum?

As a top investor in Silicon Valley, every crypto investment by Peter Thiel carries strong strategic intent. This layout in ETHZilla is not his first involvement in the Ethereum ecosystem, but rather a profound judgment on the underlying logic of the crypto market:

1. The 'institutional asset' attribute of Ethereum is highlighted.

Unlike Bitcoin's positioning as 'digital gold,' Ethereum, with its smart contract ecosystem and deflationary mechanism, is becoming the 'infrastructure for institutional allocation of crypto assets.' Peter Thiel's team chose to increase their holdings indirectly through ETHZilla, which not only avoids the compliance risks of directly holding crypto assets but also allows for enjoying the dual dividends of Ethereum price growth and ecosystem expansion — this 'curved layout' method is highly similar to traditional institutions entering Bitcoin through compliant vehicles like GBTC.

2. Betting on the 'dividend of the fusion of traditional and crypto.'

ETHZilla's online gambling business (iGaming) is a key subplot. This area inherently requires efficient value transfer and compliant settlement, and the low gas fees and high throughput characteristics of Ethereum Layer 2 can precisely address the pain points of traditional online gambling. Peter Thiel's investment essentially bets on the landing dividends of 'crypto technology transforming traditional industries,' with Ethereum being the core tool of this transformation.


It is worth noting that this is not Peter Thiel's first foray into crypto infrastructure. In mid-July, his Founders Fund held a 9.1% stake in the Bitcoin mining company BitMine Immersion Technologies, forming a dual layout of 'Bitcoin mining + Ethereum reserves' that covers the underlying assets and infrastructure of the crypto market.

3. Market reaction: Behind the stock price surge is the institutional demand for 'compliant crypto vehicles.'

The dramatic fluctuations in ETHZilla's stock price reflect the urgent demand from the market for 'compliant crypto vehicles.' Traditional capital wants to enter the crypto market, but is constrained by regulatory restrictions, facing compliance risks when directly holding crypto assets; companies like ETHZilla, which are 'transforming public companies,' offer compliant channels — by purchasing its stocks, investors can indirectly share in the growth benefits of crypto assets.


From the data, ETHZilla's financing pace is highly matched with the 'institutional preference' of fund usage:

  • $425 million private placement + $156 million convertible notes, totaling nearly $600 million in funding, is sufficient to support the purchase of tens of thousands of Ethereum (based on current prices, approximately 100,000 ETH could be purchased, accounting for 0.08% of the circulation);

  • The 'senior secured' attribute of convertible notes reduces the risks of institutional investment, which is also an important reason why seasoned investors like Peter Thiel are willing to enter.

4. Industry signal: Institutional layout enters the 'deep water zone.'

Peter Thiel's increased stake in ETHZilla is by no means an isolated event; it represents an important milestone in the institutionalization of the crypto market:

1. From 'directly buying coins' to 'ecological positioning.'

Early institutional entry often focused on directly purchasing Bitcoin and Ethereum, but now there is a greater tendency to layout 'crypto + traditional' fusion ecological vehicles. This shift indicates that institutions are no longer satisfied with 'asset appreciation' but want to participate in the transformative dividends of crypto technology on traditional industries; ETHZilla's online gambling business is a reflection of this thinking.

2. Compliant shell resources become 'hot commodities.'

Entities like ETHZilla, which have the qualifications of public companies and can raise funds through compliant channels to purchase crypto assets, are becoming a focus of competition among institutions. These vehicles can both avoid the regulatory risks of directly holding crypto assets and transmit the returns of crypto assets to traditional investors through stock price fluctuations, serving as a key node connecting the two markets.

3. The 'moat' of Ethereum is further recognized.

Peter Thiel's continuous layout is fundamentally an endorsement of the value of the Ethereum ecosystem. As the leader of smart contract platforms, Ethereum not only has a large developer ecosystem (developers account for over 60% of the entire crypto market), but its deflationary mechanism (EIP-1559 destruction rules) and staking economy (over 27 million staked after the Shanghai upgrade) also give it the attributes of an 'anti-inflation asset,' which aligns closely with institutions' demand for 'long-term value storage + growth.'

Conclusion: The 'crypto narrative' of institutions is being rewritten.

Peter Thiel's heavy investment in ETHZilla reveals a new trend: the institutionalization of the crypto market has transitioned from 'simple allocation' to the 'co-construction of ecosystems.' For ordinary investors, rather than getting tangled in 'Ethereum's short-term price fluctuations,' it is better to focus on the logic behind these 'compliant crypto vehicles' — when traditional capital begins to layout with a model of 'public companies + crypto assets,' the valuation system of the crypto market may usher in a new reconstruction.


ETHZilla's subsequent actions, especially its pace of Ethereum purchases and the implementation of its online gambling business, may become an important window for observing institutional crypto layouts. After all, in Peter Thiel's investment dictionary, 'laying out underlying trends' is always more important than 'chasing short-term hotspots.'

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