$USDC The best trading pair for USDC (USD Coin) depends on your goals. For stability and low volatility, USDC/USDT is ideal as both are stablecoins. For high liquidity and ease of entry into crypto markets, USDC/BTC and USDC/ETH are strong choices—both pairs are widely available and offer opportunities for profit during price swings. If you’re looking for DeFi opportunities, USDC/DAI is popular for yield farming and lending. On centralized exchanges like Binance or Coinbase, USDC/ETH and USDC/BTC are among the most active. Always consider trading volume, fees, and market conditions before choosing your pair.