Semler Scientific Strengthens Bitcoin Portfolio with $50 Million Acquisition, Reinforces Position Among Top BTC Treasury Holders

Semler Scientific, a prominent medical device company, has significantly expanded its cryptocurrency holdings with the purchase of $50 million worth of Bitcoin (BTC) between May 13 and May 22, 2025. This strategic acquisition increases the market value of Semler’s Bitcoin reserves to an impressive $474.4 million, cementing its position among the top 13 companies holding BTC as part of their corporate treasury.

In a regulatory filing dated May 23, Semler disclosed that it acquired a total of 455 BTC at an average price of $109,801 per Bitcoin. The company utilized funds raised through its at-the-market (ATM) equity offering program to finance the purchase. To date, Semler Scientific has successfully raised approximately $115 million in net proceeds by selling close to 3 million shares of its common stock.

Despite the bold move into digital assets, Semler Scientific’s stock experienced a slight dip of 1.36% on the day of the disclosure. However, this decline mirrors broader market trends, as the Nasdaq Composite Index, which tracks major technology companies, also dropped around 1% during the same trading session.

The BTC purchase comes amid a challenging financial period for the company. In its Q1 2025 earnings report released on May 13, Semler reported a 44% year-over-year decline in revenue. Although the company touts its Bitcoin investment strategy as a long-term value play, its share price has fallen 18% so far in 2025, according to data from Google Finance.

Nevertheless, investor interest in Bitcoin treasury strategies continues to grow. These strategies typically involve publicly traded firms leveraging equity or debt offerings to purchase and hold Bitcoin as a reserve asset. This approach has gained significant traction since MicroStrategy, led by Michael Saylor, pioneered the model in August 2020. Saylor’s BTC strategy has since inspired a wave of institutional adoption.

Bitcoin’s performance has remained robust, appreciating 181.6% year to date. Semler Scientific’s stock has also seen a 53% gain since the company initially announced its Bitcoin-focused treasury strategy in May 2024, reflecting growing investor confidence in this alternative asset allocation method.